官方QQ
官方微信
手机版
您的位置:首页 >硕士生导师>中药分析方向>详细内容

中药分析方向

范刚

fd721948fe2047f5bd805d2c954563dc.jpg

个人简介

范刚,博士、副研究员、硕士研究生导师、民族医药学院民族药物学教研室主任;成都中医药大学首批“青年英才”,四川省第十二批学术和技术带头人后备人选,四川省中医药管理局第五批学术和技术带头人后备人选,成都中医药大学藏羌彝特色民族药创新研究所副所长,四川省优秀博士学位论文获得者;为中国民族医药学会科研分会常务理事、药用资源分会理事,中华中医药学会中药分析分会委员,世界中医药学会联合会藏医药专业委员会理事;近年来,采用DNA条形码、代谢组学、微生物组学等新技术和新方法,开展了黄连、小檗皮、蒂达、圆柏等多基原中药/民族药的品种鉴定-质量评价-药效物质-作用机制研究;先后承担国家自然科学基金(青年和面上项目各1项)、国家重点研发计划子课题、四川省杰出青年培育计划、教育部博士点专项基金等项目10余项。在Pharmacological Research、Analytica Chimica Acta、Oxidative Medicine and Cellular Longevity、Frontiers in Pharmacology等杂志上发表SCI论文30余篇;培养硕士研究生4名;参编《民族药物学》、《藏药化学》等教材及专著5部;研究成果获得中国民族医药学会科技进步一等奖1项(排第2)、四川省科技进步二等奖1项(排第2)、中国民族医药学会科技进步二等奖1项(排第7)。

 

代表性成果

[1] Tong Xu#, Tingting Kuang#, Huan Du, Qi Li, Tu Feng, Yi Zhang, Gang Fan*. Magnoflorine: A review of its pharmacology, pharmacokinetics and toxicity. Pharmacological Research, 2020, 152: 104632.

[2] Qi Li , Chengcheng Zhao, Yunsen Zhang, Huan Du, Tong Xu, Xinmei Xu, Jing Zhang, Tingting Kuang, Xianrong Lai, Gang Fan*, Yi Zhang. 1H NMR-based metabolomics coupled with molecular docking reveal the anti-diabetic effects and potential active components of Berberis vernae on type 2 diabetic rats [J]. Frontiers in pharmacology, 2020, 11: 932.

[3] Wei Peng#, Huan Du#, Guangli Liu, Qing Zhang, Tingting Kuang, Zhang Wang*, Gang Fan*. Antistress effects of San-Huang-Xie-Xin decoction on restraint-stressed mice revealed by 1H NMR-based metabolomics and biochemistry analysis. Oxidative Medicine and Cellular Longevity, 2019, Vol. 2019, Article ID 5897675, 1-13.

[4] Qi Li, Hai-Jiao Li, Tong Xu, Huan Du, Chen-Lei Huan Gang, Gang Fan*, Yi Zhang. Natural medicines used in the traditional Tibetan medical system for the treatment of liver diseases[J]. Frontiers in Pharmacology, 2018, 9: 29.

[5] Tu Feng, Huan Du, Hanting Chen, Qunying Xiao, Yang He*, Gang Fan*. Comparative analysis of genetic and chemical differences between four Berberis herbs based on molecular phylogenetic and HPLC methods[J]. Biol. Pharm. Bull., 2018, 41(12): 1–5.

[6] Yue Liu#, Gang Fan#, Jing Zhang, Yi Zhang, Jingjian Li, Chao Xiong, Qi Zhang, Xiaodong Li*, Xianrong Lai*. Metabolic discrimination of sea buckthorn from different Hippophaë species by 1H NMR based metabolomics[J]. Scientific Reports, 2017, 7: 1585.

[7] Xiumei Lv#, Yan Li#, Ce Tang, Yi Zhang, Jing Zhang, Gang Fan*. Integration of HPLC-based fingerprint and quantitative analyses for differentiating botanical species and geographical growing origins of Rhizoma coptidis. Pharmaceutical Biology, 2016, 54(12): 3264-3271.

[8] Gang Fan, Wei-Zao Luo, Shang-Hua Luo, Yan Li, Xian-Li Meng, Xiang-Dong Zhou, Yi Zhang. Metabolic discrimination of Swertia mussotii and Swertia chirayita known as “Zangyinchen” in traditional Tibetan medicine by 1H NMR-based metabolomics. Journal of Pharmaceutical and Biomedical Analysis, 2014, 98, 364–370.

[9] Gang Fan, Meng Ying Zhang, Xiang Dong Zhou*, Xian Rong Lai, Qing Hong Yue, Ce Tang,Wei Zao Luo, Yi Zhang*. Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy. Analytica Chimica Acta, 2012, 747: 76–83.

[10] Gang Fan, Ling-hui Tao, Qing-hong Yue, Ting-ting Kuang, Ce Tang, Yong-dong Yang, Wei-zao Luo, Xiang-dong Zhou*, Yi Zhang*. Metabolic discrimination of Rhizoma Coptidis from different species using 1H NMR spectroscopy and principal component analysis. Planta Medica, 2012, 78(6): 641–648.  

[11] Gang Fan, Rui Deng, Lin Zhou, Xianli Meng, Tingting Kuang, Xianrong Lai, Jing Zhang*, Yi Zhang*. Development of a rapid resolution liquid chromatographic method combined with chemometrics for quality control of Angelicae dahuricae radix. Phytochemical Analysis, 2012, 23: 299–307.

 

终审:药学院管理员
【打印正文】